Researchers at the Luxembourg Institute of Health developed a new immunotherapy approach, injecting allergic mice with a mix of major cat allergen Fel d 1 in combination with high doses of CpG oligonucleotide, an adjuvant substance that improves immune response.

The mice subjected to this allergen-specific therapy showed significantly reduced signs of airway inflammation and hyper-responsiveness, lower levels of pro-allergic molecules and IgE antibodies, commonly associated with allergic responses, and higher levels of IgA and IgG antibodie antibodies, which can have anti-inflammatory properties. Read more…

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